Biochemistry MCQ Quiz Hub

1. Which of those immunoglobulin classes is mainly found in external secretions?
Ig A
Ig D
Ig M
Ig E

2. Cleavage of an IgG molecule by a specific protease can produce
an antigen-binding site and two constant regions
two heavy chain-light chain dimers
an inactive mixture of oligopeptides
two Fab fragments and one Fc fragment

3. Papain digest IgG into
two Fab fragments and one Fc fragment
three Fab fragments and two Fc fragments
two Fab fragments and two Fc fragments
three Fab fragments and three Fc fragments

4. Antibodies can be used
for the localization of proteins in the cell
for protein purification
to catalyze chemical reactions
all of the above

5. Type A blood
can be used to donate to type AB individuals
can be used to donate to type B individuals
contains type B antigens on the surface of red blood cells
can always be used to donate to an Rh+ individual

6. Which of the following are responsible for immune specificity?
Antigens
Antibodies
T lymphocytes
Macrophage

7. Which species lack immunoglobulin light chains?
Camels
Humans
cows
Buffalo

8. Monoclonal refers to
a single clone of antibody-producing cells
all the antibody molecules which are identical
the binding with same antigenic site with identical binding affinities
all of the above

9. β-Lymphocytes are often called simply
B cells
T cells
T Lymphocytes
none of these

10. IgE provides
immunity against some parasites
complement killings of the cells and phagocytosis
secretions in the body
all of the above

11. Fab fragment has
one antigen binding site
two antigen binding site
one antibody binding site
two antibody binding site

12. he main function of antibodies is to
kill all the foreign bodies
generate antigens thus conferring immunization
protect the circulatory system
chemically combine with the antigen which induces it inactivate the antigen and protect the body from disease

13. Alum is an effective adjuvant because it
disaggregates the antigen.
is immunogenic for stem cells
is immunogenic for T cells
slows the release of antigen

14. A secondary antibody is an antibody that
has been used in prior experiments
is synthetically produced
binds to another antibody
is produced in boostered animals

15. The immunoglobulin fold is
found only in IgG molecules
a β-barrel composed of a three- and a four-stranded antiparallel β-sheet
both (a) and (b)
found six times in the IgG molecule

16. Antibodies of the IgG class
consist of four subunits
are glycoproteins
are secreted into the bloodstream
all of the above

17. Each IgA antibody molecule consists of
four polypeptide chain and has two antigen binding site
two polypeptide chain and has one antigen binding site
three polypeptide chain and has two antigen binding site
two polypeptide chain and has two antigen binding site

18. Antibodies in the human immune system can identify approximately 108 different molecules Which one of the following is correct?
This diversity is generated from 108 different immunoglobin genes
Many of these molecules are self-antigens
Most of these antibodies recognize proteins
Most of these antibodies recognize small organic molecules

19. Monoclonal antibodies were first produced by
Georges Kohler and Cesar Milstein
Sarkar and Sommer
Selman Waksman
Edward Jenner and Louis Pasteur

20. A polyclonal antibody response
is produced only in response to polymeric antigens
is produced by several B cells recognizing different pitopes on the same antigen
occurs during the lag phase of the immune response
violates clonal selection

21. Structures of anti-PCP antibody shows that the tight binding of PCP to the antibody is primarily due to
hydrophobic forces
electrostatic forces.
Van der Waals forces.
none of these

22. Antigenic determinants bind to which portions of an antibody?.
Variable regions
Constant regions
Only light chains
Only heavy chains

23. he humoral immune response relies on the production of soluble proteins called
antibodies
macromolecules
lymphocytes
none of these

24. The human IgG class of antibodies is divided into
five IgG classes
two IgG classes
three IgG classes
four IgG classes